Our lab focuses on expanding our knowledge of host-immune-microbe interactions, with a specific focus on identifying host (i.e., diet) and microbial factors involved in different responses to medical and dietary therapies.
By better understanding individualized response to treatments, we can move towards developing and using personalized therapeutic programs to improve patient outcomes. We use various digital health technologies and ‘multi-omics’ techniques (i.e., metagenomics, metabolomics, metaproteomics) to explore the role that dietary intakes and the microbes residing in the gastrointestinal tract play in changing the response to therapy.
Our primary research focus revolves around investigating the nuanced interplay between nutritional and medical interventions in individuals with inflammatory bowel disease.
Specifically, our research places a significant emphasis on understanding the role of fungi in this context. Our research aims to deepen our comprehension of existing therapies and pinpoint opportunities for improvement. An example of our ongoing efforts is the OPTIMIST clinical study, which investigates the detection of biomarkers in the gut microbiome to enhance our ability to predict treatment outcomes in patients with Crohn’s disease.
Exploring the Health Benefit of Dietary Fibres We are excited to announce our upcoming Clinical Trial, lead by Dr Heather Armstrong which will explore the […]
OPTIMIST Study: Recruitment Now Underway! We are excited to announce that recruitment for the OPTIMIST study has begun in July 2024! Through this research, we […]