{"id":1653,"date":"2025-12-08T18:00:45","date_gmt":"2025-12-08T18:00:45","guid":{"rendered":"https:\/\/ibdcentrebc.ca\/lunkenlab\/?page_id=1653"},"modified":"2026-01-06T23:32:37","modified_gmt":"2026-01-06T23:32:37","slug":"dispense-t-study","status":"publish","type":"page","link":"https:\/\/ibdcentrebc.ca\/lunkenlab\/dispense-t-study\/","title":{"rendered":"Dispense-T Study"},"content":{"rendered":"\n
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Dispense-T Study<\/h3>\n\n\n\n
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Purpose of Dispense-T study<\/h2>\n\n\n\n

The DISPENSE-T study is testing whether a targeted nutritional strategy focused on a diet low in ultra processed foods (DISPENSE-T Special Diet<\/strong>) can enhance the efficacy of infliximab in children with Crohn\u2019s disease.<\/p>\n<\/div>\n\n\n\n

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Study Design<\/h2>\n\n\n\n

The study will enroll 140 children starting infliximab, who will be randomized to either continue their usual diet or follow a the DISPENSE-T Special Diet<\/strong>, with the support of a dietitian. Over the course of a year, biological samples (stool, blood, biopsies, mucosal wash), dietary data, quality-of-life measures, and clinical outcomes will be collected, and compared between the two groups.<\/p>\n\n\n\n

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What is the Dispense-T Special Diet?<\/h2>\n\n\n\n

It is a diet designed to help manage Crohn\u2019s disease by reducing inflammation in the gut. The diet limits ultra-processed foods<\/strong> and emphasizes simple, gut-friendly foods. It is structured in several phases, gradually reintroducing foods over time. Research has shown that it can help some children with Crohn\u2019s disease feel better and maintain remission.<\/p>\n<\/div>\n\n\n\n

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Who can participate<\/h2>\n\n\n\n

Children between 9 and 17 years old<\/strong> with moderate to severe active Crohn\u2019s disease (diagnosed within the past 12 months), who have never received biologic therapy and for whom the physician plans to start infliximab.<\/p>\n<\/div>\n\n\n\n

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What is Involved<\/h2>\n\n\n\n
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