{"id":1669,"date":"2026-01-06T23:44:12","date_gmt":"2026-01-06T23:44:12","guid":{"rendered":"https:\/\/ibdcentrebc.ca\/lunkenlab\/?page_id=1669"},"modified":"2026-05-07T23:36:22","modified_gmt":"2026-05-07T23:36:22","slug":"fibre-ibd-study","status":"publish","type":"page","link":"https:\/\/ibdcentrebc.ca\/lunkenlab\/fibre-ibd-study\/","title":{"rendered":"Fibre IBD Study"},"content":{"rendered":"\n<div class=\"wp-block-group has-global-padding is-layout-constrained wp-block-group-is-layout-constrained\" style=\"margin-top:-15px;padding-top:var(--wp--preset--spacing--large);padding-bottom:var(--wp--preset--spacing--large)\">\n<h3 class=\"wp-block-heading has-text-align-center has-custom-color-7-color has-text-color has-link-color has-x-large-font-size wp-elements-fe358f90c2dd4d494bcf4c5651e07479\" style=\"margin-top:0;margin-bottom:var(--wp--preset--spacing--small);margin-left:0;font-style:normal;font-weight:500;text-transform:uppercase\">Fibre IBD Study<\/h3>\n\n\n\n<figure class=\"wp-block-image aligncenter size-full is-resized has-custom-border\"><img loading=\"lazy\" decoding=\"async\" width=\"1800\" height=\"1200\" src=\"https:\/\/ibdcentrebc.ca\/lunkenlab\/wp-content\/uploads\/2024\/10\/fibreibd.png\" alt=\"\" class=\"wp-image-1395\" style=\"border-top-left-radius:24px;border-top-right-radius:24px;border-bottom-left-radius:24px;border-bottom-right-radius:24px;width:580px\" srcset=\"https:\/\/ibdcentrebc.ca\/lunkenlab\/wp-content\/uploads\/2024\/10\/fibreibd.png 1800w, https:\/\/ibdcentrebc.ca\/lunkenlab\/wp-content\/uploads\/2024\/10\/fibreibd-300x200.png 300w, https:\/\/ibdcentrebc.ca\/lunkenlab\/wp-content\/uploads\/2024\/10\/fibreibd-1024x683.png 1024w, https:\/\/ibdcentrebc.ca\/lunkenlab\/wp-content\/uploads\/2024\/10\/fibreibd-768x512.png 768w, https:\/\/ibdcentrebc.ca\/lunkenlab\/wp-content\/uploads\/2024\/10\/fibreibd-1536x1024.png 1536w\" sizes=\"auto, (max-width: 1800px) 100vw, 1800px\" \/><\/figure>\n<\/div>\n\n\n\n<div class=\"wp-block-group alignfull has-tertiary-background-color has-background has-global-padding is-layout-constrained wp-block-group-is-layout-constrained\" style=\"margin-top:0;margin-bottom:0;padding-top:var(--wp--preset--spacing--large);padding-bottom:var(--wp--preset--spacing--large)\">\n<h2 class=\"wp-block-heading\">Purpose of Fibre IBD study<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>Arm 1 (Diet Intervention):<\/strong><\/p>\n\n\n\n<p class=\"has-black-color has-text-color has-link-color has-system-font-font-family has-large-font-size wp-elements-b2641ae03b658f91768b2ff3600359c9 wp-block-paragraph\">We are exploring how different types of dietary fibre affect gut health in people with ulcerative colitis (UC).&nbsp;<\/p>\n\n\n\n<p class=\"has-black-color has-text-color has-link-color has-system-font-font-family has-large-font-size wp-elements-77a0ed71dae507ca4f7437c2252e4148 wp-block-paragraph\">We are also looking for non-UC participants to take part as controls.<\/p>\n\n\n\n<p class=\"has-black-color has-text-color has-link-color has-system-font-font-family has-large-font-size wp-elements-328ee49118498f5174ad10884ea851ce wp-block-paragraph\">Because some fibres may be harder to digest for individuals with UC, our goal is to understand whether <strong>personalized fibre and nutrition recommendations<\/strong> can:<\/p>\n\n\n\n<ul class=\"wp-block-list has-black-color has-text-color has-link-color has-system-font-font-family has-large-font-size wp-elements-323fbab6104a316d9166e930452e1dcb\">\n<li>Improve the microbes in the gut<\/li>\n\n\n\n<li>Support better nutrition<\/li>\n\n\n\n<li>Help reduce inflammation<\/li>\n<\/ul>\n\n\n\n<p class=\"has-black-color has-text-color has-link-color has-system-font-font-family has-large-font-size wp-elements-45d9bbcc9fb5651a0b65b4046691072c wp-block-paragraph\">This research will help us design more effective, individualized dietary strategies for people living with UC.<\/p>\n\n\n\n<div style=\"height:38px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>Arm 2 (Artificial Intelligence Tool Development):<\/strong><\/p>\n\n\n\n<p class=\"has-black-color has-text-color has-link-color has-system-font-font-family has-large-font-size wp-elements-f62b690cce2f97234e065e1f814f0c25 wp-block-paragraph\">Many patients with inflammatory bowel disease (IBD) describe worsening symptoms after they eat foods high in fibre. Researchers believe this may occur when the gut microbes are not breaking down some types of fibre properly, which can lead to discomfort. <\/p>\n\n\n\n<p class=\"has-black-color has-text-color has-link-color has-system-font-font-family has-large-font-size wp-elements-615f8f7136f7e7990f702a0b038384fa wp-block-paragraph\">The goal of this study is to learn more about what types of fibre a person can eat based on the profile of their gut microbes. To do this, an <strong>artificial intelligence (AI) tool<\/strong> is being developed using patient stool samples to determine which types of fibre may be <strong>helpful<\/strong> or <strong>harmful<\/strong> to include in their diet. <\/p>\n\n\n\n<p class=\"has-black-color has-text-color has-link-color has-system-font-font-family has-large-font-size wp-elements-7623f94370f21dd6b1ee7b462dae650a wp-block-paragraph\">We are looking for individuals with Crohn&#8217;s disease (CD) or UC.<\/p>\n<\/div>\n\n\n\n<div class=\"wp-block-group alignfull has-base-background-color has-background has-global-padding is-layout-constrained wp-block-group-is-layout-constrained\" style=\"padding-top:var(--wp--preset--spacing--large);padding-bottom:var(--wp--preset--spacing--large)\">\n<h2 class=\"wp-block-heading\">What is Involved<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>Arm 1 (Diet Intervention):<\/strong><\/p>\n\n\n\n<p class=\"has-black-color has-text-color has-link-color has-system-font-font-family has-large-font-size wp-elements-921dff190c2b6f49d9f423a64e0de401 wp-block-paragraph\">If you choose to participate, you will follow a personalized <strong>fibre-rich diet for 4 weeks,<\/strong> with guidance and support from a registered dietitian throughout the process.&nbsp;<\/p>\n\n\n\n<p class=\"has-black-color has-text-color has-link-color has-system-font-font-family has-large-font-size wp-elements-ace6c8ac631ab4e1e78f871254ac327e wp-block-paragraph\">As part of the diet, you will also be asked to <strong>avoid certain foods<\/strong>, including red meat, processed meats, processed dairy, and alcohol.<\/p>\n\n\n\n<p class=\"has-black-color has-text-color has-link-color has-system-font-font-family has-large-font-size wp-elements-09bdb8d87eafc956f0cef8d7ee373a10 wp-block-paragraph\">Throughout the 4-week study period, we will monitor how the diet affects your <strong>physical and mental well-being<\/strong>. This includes:<\/p>\n\n\n\n<ul class=\"wp-block-list has-black-color has-text-color has-link-color has-system-font-font-family has-large-font-size wp-elements-c61a9c645882751cc3c023ba512dcc01\">\n<li>Completing online questionnaires and 3-day food diary<\/li>\n\n\n\n<li>Providing stool samples at the beginning and end of the study<\/li>\n\n\n\n<li>A blood draw at the end of the study<\/li>\n<\/ul>\n\n\n\n<p class=\"has-black-color has-text-color has-link-color has-system-font-font-family has-large-font-size wp-elements-4ef691cd9ee2b4e185fe372048282935 wp-block-paragraph\">Additionally, during your previously scheduled colonoscopy, we will collect a small number of additional samples, such as biopsies, blood, and a mucosal wash.&nbsp;<\/p>\n\n\n\n<div style=\"height:38px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>Arm 2 (Artificial Intelligence Tool Development):<\/strong><\/p>\n\n\n\n<p class=\"has-black-color has-text-color has-link-color has-system-font-font-family has-large-font-size wp-elements-c4c068287876efe385a7aded8bd844f2 wp-block-paragraph\">If you choose to participate, you will be asked to do the following:<\/p>\n\n\n\n<ul class=\"wp-block-list has-black-color has-text-color has-link-color has-system-font-font-family has-large-font-size wp-elements-372eecd44a4da9d40eea29b3d09899b5\">\n<li>Attend a <strong>short medical history call<\/strong> about any active symptoms, routine therapies, and family history<\/li>\n\n\n\n<li>Complete <strong>online questionnaires<\/strong> about your health, diet, and general well-being<\/li>\n\n\n\n<li>Collect one <strong>stool sample<\/strong> at home<\/li>\n<\/ul>\n<\/div>\n\n\n\n<div class=\"wp-block-group alignfull has-tertiary-background-color has-background has-global-padding is-layout-constrained wp-block-group-is-layout-constrained\" style=\"margin-top:0;margin-bottom:0;padding-top:var(--wp--preset--spacing--large);padding-bottom:var(--wp--preset--spacing--large)\">\n<h2 class=\"wp-block-heading\">Who can participate<\/h2>\n\n\n\n<div class=\"wp-block-group has-custom-color-7-color has-base-background-color has-text-color has-background has-link-color wp-elements-51fc7f4cf7b1328930ae7510ad23fba8 has-global-padding is-layout-constrained wp-container-core-group-is-layout-4b7cb045 wp-block-group-is-layout-constrained\" style=\"border-radius:12px;padding-right:var(--wp--preset--spacing--small);padding-left:var(--wp--preset--spacing--small);font-size:19px;font-style:normal;font-weight:400;text-transform:none\">\n<p class=\"wp-block-paragraph\"><strong>Arm 1 (Diet Intervetion):<\/strong><\/p>\n\n\n\n<p class=\"has-black-color has-text-color has-link-color has-system-font-font-family has-large-font-size wp-elements-196385fff8483e12e7298ddc85155d3c wp-block-paragraph\"><strong>You may be able to participate in this study if you are:<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list has-black-color has-text-color has-link-color has-system-font-font-family has-large-font-size wp-elements-44d8f9e96efb36133f08dc6cdc03e0ec\">\n<li>Between the ages of 7-69<\/li>\n\n\n\n<li>Undergoing a colonoscopy<\/li>\n\n\n\n<li>On stable treatment for at least one month [only for UC patients]<\/li>\n\n\n\n<li>Clinically in remission or with mild to moderate disease \u200b[only for UC patients]<\/li>\n<\/ul>\n\n\n\n<p class=\"has-black-color has-text-color has-link-color has-system-font-font-family has-large-font-size wp-elements-74e9d1dac7e77ffb06b497de82006915 wp-block-paragraph\"><strong>You will not be eligible to participate in this study if you:<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list has-black-color has-text-color has-link-color has-system-font-font-family has-large-font-size wp-elements-79babebf34a21bb8d954a9380700bd9e\">\n<li>Used antibiotics, pro-\/pre-biotics supplements, or had an enteric infection \u200bin the last 30 days\u200b<\/li>\n\n\n\n<li>Currently taking systemic steroids\u200b<\/li>\n\n\n\n<li>History of extensive intestinal resection<\/li>\n\n\n\n<li>Presence of any non-IBD bowel conditions such as IBS, celiac, or microscopic colitis<\/li>\n\n\n\n<li>Recent history of cancer with treatment in the last 12 months<\/li>\n\n\n\n<li class=\"has-black-color has-text-color has-link-color has-system-font-font-family wp-elements-9b34ff4e4d81c927bba7d1a316947250\">Pregnant<\/li>\n<\/ul>\n\n\n\n<div style=\"height:38px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>Arm 2 (Artificial Intelligence Tool Development):<\/strong><\/p>\n\n\n\n<p class=\"has-black-color has-text-color has-link-color has-system-font-font-family has-large-font-size wp-elements-196385fff8483e12e7298ddc85155d3c wp-block-paragraph\"><strong>You may be able to participate in this study if you are:<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list has-black-color has-text-color has-link-color has-system-font-font-family has-large-font-size wp-elements-0f03701b490b72f556198fc3260ed91b\">\n<li>Between the ages of 7-69<\/li>\n\n\n\n<li>On stable treatment for at least one month<\/li>\n\n\n\n<li>Clinically in remission or with mild disease<\/li>\n<\/ul>\n\n\n\n<p class=\"has-black-color has-text-color has-link-color has-system-font-font-family has-large-font-size wp-elements-74e9d1dac7e77ffb06b497de82006915 wp-block-paragraph\"><strong>You will not be eligible to participate in this study if you:<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list has-black-color has-text-color has-link-color has-system-font-font-family has-large-font-size wp-elements-5c164085ef3949743067ffe4dfdb3826\">\n<li>Used antibiotics, pro-\/pre-biotics supplements, or had an enteric infection \u200bin the last 30 days\u200b<\/li>\n\n\n\n<li>Currently taking systemic steroids\u200b<\/li>\n\n\n\n<li>History of abdominal surgery (excluding c-section)<\/li>\n\n\n\n<li>Presence of any non-IBD bowel conditions such as IBS, celiac, or microscopic colitis<\/li>\n\n\n\n<li>Presence of a systemtic disease requiring treatment such as cancer, heart disease, or kidney failure<\/li>\n\n\n\n<li>Documented enteric infection in the last 30 days<\/li>\n\n\n\n<li class=\"has-black-color has-text-color has-link-color has-system-font-font-family wp-elements-9b34ff4e4d81c927bba7d1a316947250\">Pregnant<\/li>\n<\/ul>\n<\/div>\n<\/div>\n\n\n\n<div class=\"wp-block-group alignfull has-base-background-color has-background has-global-padding is-layout-constrained wp-block-group-is-layout-constrained\" style=\"margin-bottom:0;padding-top:var(--wp--preset--spacing--large);padding-bottom:var(--wp--preset--spacing--large)\">\n<h2 class=\"wp-block-heading\">Contact us<\/h2>\n\n\n\n<p class=\"has-text-primary-color has-text-color has-link-color has-system-font-font-family has-large-font-size wp-elements-1e306d4914f72c97a6c35400852d67fd wp-block-paragraph\" style=\"font-style:normal;font-weight:300\">If you are interested in participating in our study or would like to learn more, please contact us using the following email:<\/p>\n\n\n\n<ul style=\"font-style:normal;font-weight:300\" class=\"wp-block-list has-text-primary-color has-text-color has-link-color has-system-font-font-family has-large-font-size wp-elements-a29b0046f81eff3a3f94c30c02d9dc4b\">\n<li style=\"font-style:normal;font-weight:400\"><strong>Email:<\/strong> <a href=\"mailto:fibre.coordinator@ubc.ca\">fibre.coordinator@ubc.ca<\/a><\/li>\n<\/ul>\n<\/div>\n\n\n\n<div class=\"wp-block-group alignfull has-tertiary-background-color has-background has-global-padding is-layout-constrained wp-block-group-is-layout-constrained\" style=\"margin-bottom:0;padding-top:var(--wp--preset--spacing--large);padding-bottom:var(--wp--preset--spacing--large)\">\n<h2 class=\"wp-block-heading\">Learn More About Us<\/h2>\n\n\n\n<p class=\"has-black-color has-text-color has-link-color has-system-font-font-family has-large-font-size wp-elements-634e922ee5c68e20ec7a47a6d641acb7 wp-block-paragraph\"><a href=\"https:\/\/ibdcentrebc.ca\/lunkenlab\/research\/\">Lunken Lab<\/a><\/p>\n<\/div>\n","protected":false},"excerpt":{"rendered":"<p>Fibre IBD Study Purpose of Fibre IBD study Arm 1 (Diet Intervention): We are exploring how different types of dietary fibre affect gut health in [&hellip;]<\/p>\n","protected":false},"author":3,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"footnotes":"","_links_to":"","_links_to_target":""},"class_list":["post-1669","page","type-page","status-publish","hentry"],"aioseo_notices":[],"_links":{"self":[{"href":"https:\/\/ibdcentrebc.ca\/lunkenlab\/wp-json\/wp\/v2\/pages\/1669","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/ibdcentrebc.ca\/lunkenlab\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/ibdcentrebc.ca\/lunkenlab\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/ibdcentrebc.ca\/lunkenlab\/wp-json\/wp\/v2\/users\/3"}],"replies":[{"embeddable":true,"href":"https:\/\/ibdcentrebc.ca\/lunkenlab\/wp-json\/wp\/v2\/comments?post=1669"}],"version-history":[{"count":9,"href":"https:\/\/ibdcentrebc.ca\/lunkenlab\/wp-json\/wp\/v2\/pages\/1669\/revisions"}],"predecessor-version":[{"id":1853,"href":"https:\/\/ibdcentrebc.ca\/lunkenlab\/wp-json\/wp\/v2\/pages\/1669\/revisions\/1853"}],"wp:attachment":[{"href":"https:\/\/ibdcentrebc.ca\/lunkenlab\/wp-json\/wp\/v2\/media?parent=1669"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}