{"id":1669,"date":"2026-01-06T23:44:12","date_gmt":"2026-01-06T23:44:12","guid":{"rendered":"https:\/\/ibdcentrebc.ca\/lunkenlab\/?page_id=1669"},"modified":"2026-06-15T21:16:51","modified_gmt":"2026-06-15T21:16:51","slug":"fibre-ibd-study","status":"publish","type":"page","link":"https:\/\/ibdcentrebc.ca\/lunkenlab\/fibre-ibd-study\/","title":{"rendered":"Fibre IBD Study"},"content":{"rendered":"\n<div class=\"wp-block-group has-global-padding is-layout-constrained wp-block-group-is-layout-constrained\" style=\"margin-top:-15px;padding-top:var(--wp--preset--spacing--large);padding-bottom:var(--wp--preset--spacing--large)\">\n<h3 class=\"wp-block-heading has-text-align-center has-custom-color-7-color has-text-color has-link-color has-x-large-font-size wp-elements-1\" style=\"margin-top:0;margin-bottom:var(--wp--preset--spacing--small);margin-left:0;font-style:normal;font-weight:500;text-transform:uppercase\">Fibre IBD Study<\/h3>\n\n\n\n<figure class=\"wp-block-image aligncenter size-full is-resized has-custom-border\"><img loading=\"lazy\" decoding=\"async\" width=\"1800\" height=\"1200\" src=\"https:\/\/ibdcentrebc.ca\/lunkenlab\/wp-content\/uploads\/2024\/10\/fibreibd.png\" alt=\"\" class=\"wp-image-1395\" style=\"border-top-left-radius:24px;border-top-right-radius:24px;border-bottom-left-radius:24px;border-bottom-right-radius:24px;width:580px\" srcset=\"https:\/\/ibdcentrebc.ca\/lunkenlab\/wp-content\/uploads\/2024\/10\/fibreibd.png 1800w, https:\/\/ibdcentrebc.ca\/lunkenlab\/wp-content\/uploads\/2024\/10\/fibreibd-300x200.png 300w, https:\/\/ibdcentrebc.ca\/lunkenlab\/wp-content\/uploads\/2024\/10\/fibreibd-1024x683.png 1024w, https:\/\/ibdcentrebc.ca\/lunkenlab\/wp-content\/uploads\/2024\/10\/fibreibd-768x512.png 768w, https:\/\/ibdcentrebc.ca\/lunkenlab\/wp-content\/uploads\/2024\/10\/fibreibd-1536x1024.png 1536w\" sizes=\"auto, (max-width: 1800px) 100vw, 1800px\" \/><\/figure>\n<\/div>\n\n\n\n<div class=\"wp-block-group alignfull has-tertiary-background-color has-background has-global-padding is-layout-constrained wp-block-group-is-layout-constrained\" style=\"margin-top:0;margin-bottom:0;padding-top:var(--wp--preset--spacing--large);padding-bottom:var(--wp--preset--spacing--large)\">\n<h2 class=\"wp-block-heading\">Purpose of Fibre IBD study<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>Arm 1 (Diet Intervention):<\/strong><\/p>\n\n\n\n<p class=\"has-black-color has-text-color has-link-color has-system-font-font-family has-large-font-size wp-elements-2 wp-block-paragraph\">We are exploring how different types of dietary fibre affect gut health in people with ulcerative colitis (UC).&nbsp;<\/p>\n\n\n\n<p class=\"has-black-color has-text-color has-link-color has-system-font-font-family has-large-font-size wp-elements-3 wp-block-paragraph\">We are also looking for non-UC participants to take part as controls.<\/p>\n\n\n\n<p class=\"has-black-color has-text-color has-link-color has-system-font-font-family has-large-font-size wp-elements-4 wp-block-paragraph\">Because some fibres may be harder to digest for individuals with UC, our goal is to understand whether <strong>personalized fibre and nutrition recommendations<\/strong> can:<\/p>\n\n\n\n<ul class=\"wp-block-list has-black-color has-text-color has-link-color has-system-font-font-family has-large-font-size wp-elements-5\">\n<li>Improve the microbes in the gut<\/li>\n\n\n\n<li>Support better nutrition<\/li>\n\n\n\n<li>Help reduce inflammation<\/li>\n<\/ul>\n\n\n\n<p class=\"has-black-color has-text-color has-link-color has-system-font-font-family has-large-font-size wp-elements-6 wp-block-paragraph\">This research will help us design more effective, individualized dietary strategies for people living with UC.<\/p>\n\n\n\n<div style=\"height:38px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>Arm 2 (Artificial Intelligence Tool Development):<\/strong><\/p>\n\n\n\n<p class=\"has-black-color has-text-color has-link-color has-system-font-font-family has-large-font-size wp-elements-7 wp-block-paragraph\">Many patients with inflammatory bowel disease (IBD) describe worsening symptoms after they eat foods high in fibre. Researchers believe this may occur when the gut microbes are not breaking down some types of fibre properly, which can lead to discomfort. <\/p>\n\n\n\n<p class=\"has-black-color has-text-color has-link-color has-system-font-font-family has-large-font-size wp-elements-8 wp-block-paragraph\">The goal of this study is to learn more about what types of fibre a person can eat based on the profile of their gut microbes. To do this, an <strong>artificial intelligence (AI) tool<\/strong> is being developed using patient stool samples to determine which types of fibre may be <strong>helpful<\/strong> or <strong>harmful<\/strong> to include in their diet. <\/p>\n\n\n\n<p class=\"has-black-color has-text-color has-link-color has-system-font-font-family has-large-font-size wp-elements-9 wp-block-paragraph\">We are looking for individuals with Crohn&#8217;s disease (CD) or UC.<\/p>\n<\/div>\n\n\n\n<div class=\"wp-block-group alignfull has-base-background-color has-background has-global-padding is-layout-constrained wp-block-group-is-layout-constrained\" style=\"padding-top:var(--wp--preset--spacing--large);padding-bottom:var(--wp--preset--spacing--large)\">\n<h2 class=\"wp-block-heading\">What is Involved<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>Arm 1 (Diet Intervention):<\/strong><\/p>\n\n\n\n<p class=\"has-black-color has-text-color has-link-color has-system-font-font-family has-large-font-size wp-elements-10 wp-block-paragraph\">If you choose to participate, you will follow a personalized <strong>fibre-rich diet for 4 weeks,<\/strong> with guidance and support from a registered dietitian throughout the process.&nbsp;<\/p>\n\n\n\n<p class=\"has-black-color has-text-color has-link-color has-system-font-font-family has-large-font-size wp-elements-11 wp-block-paragraph\">As part of the diet, you will also be asked to <strong>avoid certain foods<\/strong>, including red meat, processed meats, processed dairy, and alcohol.<\/p>\n\n\n\n<p class=\"has-black-color has-text-color has-link-color has-system-font-font-family has-large-font-size wp-elements-12 wp-block-paragraph\">Throughout the 4-week study period, we will monitor how the diet affects your <strong>physical and mental well-being<\/strong>. This includes:<\/p>\n\n\n\n<ul class=\"wp-block-list has-black-color has-text-color has-link-color has-system-font-font-family has-large-font-size wp-elements-13\">\n<li>Completing online questionnaires and 3-day food diary<\/li>\n\n\n\n<li>Providing stool samples at the beginning and end of the study<\/li>\n\n\n\n<li>A blood draw at the end of the study<\/li>\n<\/ul>\n\n\n\n<p class=\"has-black-color has-text-color has-link-color has-system-font-font-family has-large-font-size wp-elements-14 wp-block-paragraph\">Additionally, during your previously scheduled colonoscopy, we will collect a small number of additional samples, such as biopsies, blood, and a mucosal wash.&nbsp;<\/p>\n\n\n\n<div style=\"height:38px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>Arm 2 (Artificial Intelligence Tool Development):<\/strong><\/p>\n\n\n\n<p class=\"has-black-color has-text-color has-link-color has-system-font-font-family has-large-font-size wp-elements-15 wp-block-paragraph\">If you choose to participate, you will be asked to do the following:<\/p>\n\n\n\n<ul class=\"wp-block-list has-black-color has-text-color has-link-color has-system-font-font-family has-large-font-size wp-elements-16\">\n<li>Attend a <strong>short medical history call<\/strong> about any active symptoms, routine therapies, and family history<\/li>\n\n\n\n<li>Complete <strong>online questionnaires<\/strong> about your health, diet, and general well-being<\/li>\n\n\n\n<li>Collect one <strong>stool sample<\/strong> at home<\/li>\n<\/ul>\n<\/div>\n\n\n\n<div class=\"wp-block-group alignfull has-tertiary-background-color has-background has-global-padding is-layout-constrained wp-block-group-is-layout-constrained\" style=\"margin-top:0;margin-bottom:0;padding-top:var(--wp--preset--spacing--large);padding-bottom:var(--wp--preset--spacing--large)\">\n<h2 class=\"wp-block-heading\">Who can participate<\/h2>\n\n\n\n<div class=\"wp-block-group has-custom-color-7-color has-base-background-color has-text-color has-background has-link-color wp-elements-17 has-global-padding is-layout-constrained wp-container-core-group-is-layout-4b7cb045 wp-block-group-is-layout-constrained\" style=\"border-radius:12px;padding-right:var(--wp--preset--spacing--small);padding-left:var(--wp--preset--spacing--small);font-size:19px;font-style:normal;font-weight:400;text-transform:none\">\n<p class=\"wp-block-paragraph\"><strong>Arm 1 (Diet Intervetion):<\/strong><\/p>\n\n\n\n<p class=\"has-black-color has-text-color has-link-color has-system-font-font-family has-large-font-size wp-elements-18 wp-block-paragraph\"><strong>You may be able to participate in this study if you are:<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list has-black-color has-text-color has-link-color has-system-font-font-family has-large-font-size wp-elements-19\">\n<li>Between the ages of 7-69<\/li>\n\n\n\n<li>Undergoing a colonoscopy<\/li>\n\n\n\n<li>On stable treatment for at least one month [only for UC patients]<\/li>\n\n\n\n<li>Clinically in remission or with mild to moderate disease \u200b[only for UC patients]<\/li>\n<\/ul>\n\n\n\n<p class=\"has-black-color has-text-color has-link-color has-system-font-font-family has-large-font-size wp-elements-20 wp-block-paragraph\"><strong>You will not be eligible to participate in this study if you:<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list has-black-color has-text-color has-link-color has-system-font-font-family has-large-font-size wp-elements-21\">\n<li>Used antibiotics, pro-\/pre-biotics supplements, or had an enteric infection \u200bin the last 30 days\u200b<\/li>\n\n\n\n<li>Currently taking systemic steroids\u200b<\/li>\n\n\n\n<li>History of extensive intestinal resection<\/li>\n\n\n\n<li>Presence of any non-IBD bowel conditions such as IBS, celiac, or microscopic colitis<\/li>\n\n\n\n<li>Recent history of cancer with treatment in the last 12 months<\/li>\n\n\n\n<li class=\"has-black-color has-text-color has-link-color has-system-font-font-family wp-elements-22\">Pregnant<\/li>\n<\/ul>\n\n\n\n<div style=\"height:38px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>Arm 2 (Artificial Intelligence Tool Development):<\/strong><\/p>\n\n\n\n<p class=\"has-black-color has-text-color has-link-color has-system-font-font-family has-large-font-size wp-elements-23 wp-block-paragraph\"><strong>You may be able to participate in this study if you are:<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list has-black-color has-text-color has-link-color has-system-font-font-family has-large-font-size wp-elements-24\">\n<li>Between the ages of 7-69<\/li>\n\n\n\n<li>On stable treatment for at least one month<\/li>\n\n\n\n<li>Clinically in remission or with mild disease<\/li>\n<\/ul>\n\n\n\n<p class=\"has-black-color has-text-color has-link-color has-system-font-font-family has-large-font-size wp-elements-25 wp-block-paragraph\"><strong>You will not be eligible to participate in this study if you:<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list has-black-color has-text-color has-link-color has-system-font-font-family has-large-font-size wp-elements-26\">\n<li>Used antibiotics, pro-\/pre-biotics supplements, or had an enteric infection \u200bin the last 30 days\u200b<\/li>\n\n\n\n<li>Currently taking systemic steroids\u200b<\/li>\n\n\n\n<li>History of abdominal surgery (excluding c-section)<\/li>\n\n\n\n<li>Presence of any non-IBD bowel conditions such as IBS, celiac, or microscopic colitis<\/li>\n\n\n\n<li>Presence of a systemtic disease requiring treatment such as cancer, heart disease, or kidney failure<\/li>\n\n\n\n<li>Documented enteric infection in the last 30 days<\/li>\n\n\n\n<li class=\"has-black-color has-text-color has-link-color has-system-font-font-family wp-elements-27\">Pregnant<\/li>\n<\/ul>\n<\/div>\n<\/div>\n\n\n\n<div class=\"wp-block-group alignfull has-base-background-color has-background has-global-padding is-layout-constrained wp-block-group-is-layout-constrained\" style=\"margin-bottom:0;padding-top:var(--wp--preset--spacing--large);padding-bottom:var(--wp--preset--spacing--large)\">\n<h2 class=\"wp-block-heading\">Contact us<\/h2>\n\n\n\n<p class=\"has-text-primary-color has-text-color has-link-color has-system-font-font-family has-large-font-size wp-elements-28 wp-block-paragraph\" style=\"font-style:normal;font-weight:300\">If you are interested in participating in our study or would like to learn more, please contact us using the following email:<\/p>\n\n\n\n<ul style=\"font-style:normal;font-weight:300\" class=\"wp-block-list has-text-primary-color has-text-color has-link-color has-system-font-font-family has-large-font-size wp-elements-29\">\n<li style=\"font-style:normal;font-weight:400\"><strong>Email:<\/strong> <a href=\"mailto:fibre.coordinator@ubc.ca\">fibre.coordinator@ubc.ca<\/a><\/li>\n<\/ul>\n<\/div>\n\n\n\n<div class=\"wp-block-group alignfull has-tertiary-background-color has-background has-global-padding is-layout-constrained wp-block-group-is-layout-constrained\" style=\"margin-bottom:0;padding-top:var(--wp--preset--spacing--large);padding-bottom:var(--wp--preset--spacing--large)\">\n<h2 class=\"wp-block-heading\">Learn More About Us<\/h2>\n\n\n\n<p class=\"has-black-color has-text-color has-link-color has-system-font-font-family has-large-font-size wp-elements-30 wp-block-paragraph\"><a href=\"https:\/\/ibdcentrebc.ca\/lunkenlab\/research\/\">Lunken Lab<\/a><\/p>\n<\/div>\n\n\n\n<div class=\"wp-block-group alignwide has-custom-color-7-color has-text-color has-link-color wp-elements-31 has-global-padding is-layout-constrained wp-block-group-is-layout-constrained\">\n<h2 class=\"wp-block-heading has-text-align-center\" style=\"margin-bottom:var(--wp--preset--spacing--medium)\"><strong>Interested in Making a Difference for People Living with IBD?<\/strong><\/h2>\n\n\n\n<figure class=\"wp-block-image aligncenter size-large is-resized\"><img loading=\"lazy\" decoding=\"async\" width=\"945\" height=\"630\" src=\"https:\/\/ibdcentrebc.ca\/lunkenlab\/wp-content\/uploads\/2026\/05\/Donate-3-edited.png\" alt=\"\" class=\"wp-image-1898\" style=\"aspect-ratio:1.499243533430942;width:258px;height:auto\" srcset=\"https:\/\/ibdcentrebc.ca\/lunkenlab\/wp-content\/uploads\/2026\/05\/Donate-3-edited.png 945w, https:\/\/ibdcentrebc.ca\/lunkenlab\/wp-content\/uploads\/2026\/05\/Donate-3-edited-300x200.png 300w, https:\/\/ibdcentrebc.ca\/lunkenlab\/wp-content\/uploads\/2026\/05\/Donate-3-edited-768x512.png 768w\" sizes=\"auto, (max-width: 945px) 100vw, 945px\" \/><\/figure>\n\n\n\n<p class=\"has-text-align-center wp-block-paragraph\">Your support will help advance research aimed at developing personalized nutrition strategies for people with ulcerative colitis and Crohn&#8217;s disease. Donations will directly support participant recruitment, sample collection and analysis, and the development of innovative tools, including artificial intelligence approaches, to better understand how gut microbes respond to different types of dietary fibre.<\/p>\n\n\n\n<p class=\"has-text-align-center wp-block-paragraph\">Together, we can help create more personalized, effective dietary recommendations and improve the quality of life of people living with IBD.<\/p>\n\n\n\n<div class=\"wp-block-buttons is-content-justification-center is-layout-flex wp-container-core-buttons-is-layout-4927ffd3 wp-block-buttons-is-layout-flex\">\n<div class=\"wp-block-button\"><a class=\"wp-block-button__link wp-element-button\" href=\"https:\/\/donate.give.ubc.ca\/page\/68038\/donate\/1?transaction.dirgift=Dr.%20Genelle%20Lunken%27s%20Lab%20Donations%20Supporting%20Gut,%20Nutrition%20and%20Microbiome%20Research%20Fund%20G4588\">Support Our Research<\/a><\/div>\n<\/div>\n<\/div>\n","protected":false},"excerpt":{"rendered":"<p>Fibre IBD Study Purpose of Fibre IBD study Arm 1 (Diet Intervention): We are exploring how different types of dietary fibre affect gut health in [&hellip;]<\/p>\n","protected":false},"author":3,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"footnotes":"","_links_to":"","_links_to_target":""},"class_list":["post-1669","page","type-page","status-publish","hentry"],"aioseo_notices":[],"_links":{"self":[{"href":"https:\/\/ibdcentrebc.ca\/lunkenlab\/wp-json\/wp\/v2\/pages\/1669","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/ibdcentrebc.ca\/lunkenlab\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/ibdcentrebc.ca\/lunkenlab\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/ibdcentrebc.ca\/lunkenlab\/wp-json\/wp\/v2\/users\/3"}],"replies":[{"embeddable":true,"href":"https:\/\/ibdcentrebc.ca\/lunkenlab\/wp-json\/wp\/v2\/comments?post=1669"}],"version-history":[{"count":11,"href":"https:\/\/ibdcentrebc.ca\/lunkenlab\/wp-json\/wp\/v2\/pages\/1669\/revisions"}],"predecessor-version":[{"id":1960,"href":"https:\/\/ibdcentrebc.ca\/lunkenlab\/wp-json\/wp\/v2\/pages\/1669\/revisions\/1960"}],"wp:attachment":[{"href":"https:\/\/ibdcentrebc.ca\/lunkenlab\/wp-json\/wp\/v2\/media?parent=1669"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}