{"id":1693,"date":"2026-02-08T08:37:55","date_gmt":"2026-02-08T08:37:55","guid":{"rendered":"https:\/\/ibdcentrebc.ca\/lunkenlab\/?page_id=1693"},"modified":"2026-05-22T00:32:39","modified_gmt":"2026-05-22T00:32:39","slug":"calina-ibd-study","status":"publish","type":"page","link":"https:\/\/ibdcentrebc.ca\/lunkenlab\/calina-ibd-study\/","title":{"rendered":"Calina-IBD Study"},"content":{"rendered":"\n<div class=\"wp-block-group has-global-padding is-layout-constrained wp-block-group-is-layout-constrained\" style=\"margin-top:-15px;padding-top:var(--wp--preset--spacing--x-small);padding-bottom:var(--wp--preset--spacing--x-small)\">\n<h3 class=\"wp-block-heading has-text-align-center has-custom-color-7-color has-text-color has-link-color has-xx-large-font-size wp-elements-85ea66ea121b7383e4d0e73acaec9ef2\" style=\"margin-top:var(--wp--preset--spacing--xx-small);margin-bottom:0;margin-left:0;font-style:normal;font-weight:500;text-transform:uppercase\">Calina-IBd Study<\/h3>\n\n\n\n<figure class=\"wp-block-image aligncenter size-full is-resized\"><img loading=\"lazy\" decoding=\"async\" width=\"906\" height=\"522\" src=\"https:\/\/ibdcentrebc.ca\/lunkenlab\/wp-content\/uploads\/2026\/02\/image.png\" alt=\"\" class=\"wp-image-1696\" style=\"aspect-ratio:1.7356337962313555;width:403px;height:auto\" srcset=\"https:\/\/ibdcentrebc.ca\/lunkenlab\/wp-content\/uploads\/2026\/02\/image.png 906w, https:\/\/ibdcentrebc.ca\/lunkenlab\/wp-content\/uploads\/2026\/02\/image-300x173.png 300w, https:\/\/ibdcentrebc.ca\/lunkenlab\/wp-content\/uploads\/2026\/02\/image-768x442.png 768w\" sizes=\"auto, (max-width: 906px) 100vw, 906px\" \/><\/figure>\n<\/div>\n\n\n\n<div class=\"wp-block-group alignfull has-tertiary-background-color has-background has-global-padding is-layout-constrained wp-block-group-is-layout-constrained\" style=\"margin-top:0;margin-bottom:0;padding-top:var(--wp--preset--spacing--medium);padding-bottom:var(--wp--preset--spacing--medium)\">\n<h2 class=\"wp-block-heading\">Purpose of THe Study<\/h2>\n\n\n\n<p class=\"has-text-primary-color has-text-color has-link-color has-system-font-font-family has-large-font-size wp-elements-b4d8b89f4f00ab59cdc6c2c80a39934f wp-block-paragraph\" style=\"font-style:normal;font-weight:400\">The goal of this observational pilot study is to explore how inflammatory bowel disease (IBD) during pregnancy may influence the mother\/birthing parent and infant gut inflammation and overall health. The study focuses on pregnant adults living in British Columbia, Canada.<\/p>\n\n\n\n<div class=\"wp-block-file\"><a id=\"wp-block-file--media-16085e35-70b6-4c0b-89fa-ac69b16f4e93\" href=\"https:\/\/ibdcentrebc.ca\/lunkenlab\/wp-content\/uploads\/2026\/03\/Brochure-2.pdf\" target=\"_blank\" rel=\"noreferrer noopener\">Study Brochure<\/a><a href=\"https:\/\/ibdcentrebc.ca\/lunkenlab\/wp-content\/uploads\/2026\/03\/Brochure-2.pdf\" class=\"wp-block-file__button wp-element-button\" download aria-describedby=\"wp-block-file--media-16085e35-70b6-4c0b-89fa-ac69b16f4e93\">Download<\/a><\/div>\n<\/div>\n\n\n\n<div class=\"wp-block-group alignfull has-global-padding is-layout-constrained wp-block-group-is-layout-constrained\" style=\"margin-top:0;margin-bottom:0;padding-top:var(--wp--preset--spacing--medium);padding-bottom:var(--wp--preset--spacing--medium)\">\n<h2 class=\"wp-block-heading\">Goals of calina-IBD study<\/h2>\n\n\n\n<p class=\"has-text-primary-color has-text-color has-link-color has-system-font-font-family has-large-font-size wp-elements-dc5d095b164c107d33fb1e1e942b2a59 wp-block-paragraph\" style=\"font-style:normal;font-weight:400\">The main questions this study seeks to answer are:<\/p>\n\n\n\n<ul style=\"font-style:normal;font-weight:400\" class=\"wp-block-list has-text-primary-color has-text-color has-link-color has-system-font-font-family has-large-font-size wp-elements-8e2fe547051bf213d00f273479e3fc48\">\n<li>How do gut microbiome profiles and dietary patterns during pregnancy differ between mothers\/birthing parents with and without IBD?<\/li>\n\n\n\n<li>Are certain maternal\/birthing parent gut bacteria or dietary habits linked to higher levels of gut inflammation in infants, as measured by fecal calprotectin (FCP)?<\/li>\n\n\n\n<li>How do infant gut microbiome and early diet (breastmilk) contribute to inflammation in the first year of life?<\/li>\n\n\n\n<li>How do sugars in breastmilk differ between mothers\/birthing parents with and without IBD, and how might these sugars affect the infant\u2019s gut bacteria and inflammation?<\/li>\n<\/ul>\n\n\n\n<p class=\"has-text-primary-color has-text-color has-link-color has-system-font-font-family has-large-font-size wp-elements-0738f2bfe8b005228d106650566bc07c wp-block-paragraph\" style=\"font-style:normal;font-weight:400\">Researchers aim to identify diet, microbiome, and breastmilk-related factors that may contribute to your infant gut inflammation. These findings could help guide future dietary interventions to support healthier outcomes for mothers\/birthing parent and their infant.<\/p>\n\n\n\n<div class=\"wp-block-buttons alignwide is-content-justification-center is-layout-flex wp-container-core-buttons-is-layout-4927ffd3 wp-block-buttons-is-layout-flex\">\n<div class=\"wp-block-button hvr-grow is-style-outline is-style-outline--1\"><a class=\"wp-block-button__link has-pale-cyan-blue-color has-text-color has-link-color has-text-align-center wp-element-button\" href=\"https:\/\/rc.bcchr.ca\/redcap\/surveys\/?s=483LNYAJRF49XWPH\" target=\"_blank\" rel=\"noreferrer noopener\">Click Here To Participate<\/a><\/div>\n<\/div>\n<\/div>\n\n\n\n<div class=\"wp-block-group alignfull has-tertiary-background-color has-background has-global-padding is-layout-constrained wp-block-group-is-layout-constrained\" style=\"margin-top:0;margin-bottom:0;padding-top:var(--wp--preset--spacing--large);padding-bottom:var(--wp--preset--spacing--large)\">\n<h2 class=\"wp-block-heading\">What is involved?<\/h2>\n\n\n\n<figure class=\"wp-block-image aligncenter size-large\"><img loading=\"lazy\" decoding=\"async\" width=\"1545\" height=\"1029\" src=\"https:\/\/ibdcentrebc.ca\/lunkenlab\/wp-content\/uploads\/2026\/03\/Untitled-8.5-x-11-in-1-edited.png\" alt=\"\" class=\"wp-image-1775\" srcset=\"https:\/\/ibdcentrebc.ca\/lunkenlab\/wp-content\/uploads\/2026\/03\/Untitled-8.5-x-11-in-1-edited.png 1545w, https:\/\/ibdcentrebc.ca\/lunkenlab\/wp-content\/uploads\/2026\/03\/Untitled-8.5-x-11-in-1-edited-300x200.png 300w, https:\/\/ibdcentrebc.ca\/lunkenlab\/wp-content\/uploads\/2026\/03\/Untitled-8.5-x-11-in-1-edited-1024x682.png 1024w, https:\/\/ibdcentrebc.ca\/lunkenlab\/wp-content\/uploads\/2026\/03\/Untitled-8.5-x-11-in-1-edited-768x512.png 768w, https:\/\/ibdcentrebc.ca\/lunkenlab\/wp-content\/uploads\/2026\/03\/Untitled-8.5-x-11-in-1-edited-1536x1023.png 1536w\" sizes=\"auto, (max-width: 1545px) 100vw, 1545px\" \/><\/figure>\n\n\n\n<p class=\"has-text-primary-color has-text-color has-link-color has-system-font-font-family has-large-font-size wp-elements-c01459f86bc52f1ca0601805bee246a4 wp-block-paragraph\" style=\"font-style:normal;font-weight:400\">These samples and records will help researchers understand how maternal IBD, diet, microbiome, and breastmilk composition may influence infant gut inflammation and development. All materials will be provided and shipped by the research team, and participation can be completed from home.<\/p>\n<\/div>\n\n\n\n<div class=\"wp-block-group alignfull has-base-background-color has-background has-global-padding is-layout-constrained wp-block-group-is-layout-constrained\" style=\"padding-top:var(--wp--preset--spacing--large);padding-bottom:var(--wp--preset--spacing--small)\">\n<h2 class=\"wp-block-heading\">Who can participate<\/h2>\n\n\n\n<p class=\"has-text-primary-color has-text-color has-link-color has-system-font-font-family has-large-font-size wp-elements-be39d34d37b763839a5fb99d94c7a460 wp-block-paragraph\" style=\"font-style:normal;font-weight:500\"><strong>Eligibility<\/strong>:<\/p>\n\n\n\n<ul style=\"font-style:normal;font-weight:400\" class=\"wp-block-list has-text-primary-color has-text-color has-link-color has-system-font-font-family has-large-font-size wp-elements-829db0e3f658fb96a591fd83ca21f94f\">\n<li><strong>Ages<\/strong> <strong>19 years<\/strong> or older<\/li>\n\n\n\n<li>Confirmed pregnancy <strong>before 35 weeks<\/strong> of gestation<\/li>\n\n\n\n<li><strong>For IBD group:<\/strong> Confirmed diagnosis of Crohn\u2019s Disease, Ulcerative Colitis&nbsp;<\/li>\n\n\n\n<li>Interested in learning about bacteria in your gut&nbsp;<\/li>\n\n\n\n<li><strong>For control:<\/strong> Do not have a diagnosis of IBD (serving as comparison group)&nbsp;<\/li>\n\n\n\n<li>Wanting to help advance research on maternal dietary interventions and early prevention for infants at high risk of inflammatory bowel disease<\/li>\n<\/ul>\n\n\n\n<p class=\"has-text-primary-color has-text-color has-link-color has-system-font-font-family has-large-font-size wp-elements-07459314d50b06f9e0662adb40d70b08 wp-block-paragraph\" style=\"font-style:normal;font-weight:500\"><strong>Exclusion:<\/strong><\/p>\n\n\n\n<ul style=\"font-style:normal;font-weight:400\" class=\"wp-block-list has-text-primary-color has-text-color has-link-color has-system-font-font-family has-large-font-size wp-elements-87aa11d010d7aa2adabbcfd1ff2bc102\">\n<li>Travel outside of Canada and the United States<strong> in the month prior <\/strong>to first sample collection&nbsp;<\/li>\n\n\n\n<li><strong>Inability<\/strong> to provide consent<\/li>\n\n\n\n<li><strong>Previous gastrointestinal cancer<\/strong> or bowel surgery<\/li>\n\n\n\n<li><strong>Renal disease<\/strong>&nbsp;<\/li>\n\n\n\n<li><strong>HIV\/AIDS<\/strong> or other serious infection<\/li>\n\n\n\n<li><strong>Fetal chromosomal<\/strong> or structural abnormalities&nbsp;<\/li>\n\n\n\n<li><strong>Other immune-mediated diseases<\/strong> (e.g., multiple sclerosis, rheumatoid arthritis, primary sclerosing cholangitis)<\/li>\n\n\n\n<li>Prebiotic, probiotic or postbiotic supplements <strong>in the month prior<\/strong> to first sample collection&nbsp;<\/li>\n\n\n\n<li><strong>Gastroenteritis during<\/strong> or 1 month before the first sample collection&nbsp;<\/li>\n<\/ul>\n<\/div>\n\n\n\n<div class=\"wp-block-group alignfull has-tertiary-background-color has-background has-global-padding is-layout-constrained wp-block-group-is-layout-constrained\" style=\"margin-bottom:0;padding-top:var(--wp--preset--spacing--large);padding-bottom:var(--wp--preset--spacing--large)\">\n<h2 class=\"wp-block-heading\">How the CALINA-IBD Study Could Benefit You<\/h2>\n\n\n\n<ul style=\"font-style:normal;font-weight:400\" class=\"wp-block-list has-text-primary-color has-text-color has-link-color has-system-font-font-family has-large-font-size wp-elements-2df0aa2b11939b12c165b68a9d0a6aac\">\n<li>Get free access to the <a href=\"https:\/\/rxfood.com\/\" target=\"_blank\" rel=\"noopener\" title=\"\">RxFood<\/a> App and receive personalized reports of your dietary intake at the end of the study (See example below)<\/li>\n\n\n\n<li>Learn about your gut microbiome and your baby\u2019s microbiome<\/li>\n\n\n\n<li>Gain insight into your baby\u2019s gut inflammation (measured by fecal calprotectin) <\/li>\n\n\n\n<li>Receive two $25 gift cards of your choice (e.g., Shoppers, Save-On-Foods, Amazon, Lululemon)<\/li>\n\n\n\n<li>Help us better understand the connections between diet, gut health, and early development <\/li>\n<\/ul>\n\n\n\n<div class=\"wp-block-file\"><a id=\"wp-block-file--media-5b1ccd8d-52d9-46d9-aef7-45f40fdd5863\" href=\"https:\/\/ibdcentrebc.ca\/lunkenlab\/wp-content\/uploads\/2026\/03\/RXFood-Report.pdf\" target=\"_blank\" rel=\"noreferrer noopener\">RXFood Report Example<\/a><a href=\"https:\/\/ibdcentrebc.ca\/lunkenlab\/wp-content\/uploads\/2026\/03\/RXFood-Report.pdf\" class=\"wp-block-file__button wp-element-button\" download aria-describedby=\"wp-block-file--media-5b1ccd8d-52d9-46d9-aef7-45f40fdd5863\">Download<\/a><\/div>\n<\/div>\n\n\n\n<div class=\"wp-block-group alignfull has-base-background-color has-background has-global-padding is-layout-constrained wp-block-group-is-layout-constrained\" style=\"padding-top:var(--wp--preset--spacing--x-small);padding-bottom:var(--wp--preset--spacing--small)\">\n<h2 class=\"wp-block-heading\">Contact us<\/h2>\n\n\n\n<p class=\"has-text-primary-color has-text-color has-link-color has-system-font-font-family has-large-font-size wp-elements-10d9be192482827b7b84f422ebec918d wp-block-paragraph\" style=\"font-style:normal;font-weight:300\">If you are interested in participating in our study or would like to learn more, please contact us using the following methods below:<\/p>\n\n\n\n<ul style=\"font-style:normal;font-weight:300\" class=\"wp-block-list has-text-primary-color has-text-color has-link-color has-system-font-font-family has-large-font-size wp-elements-026a93443066f04a8efde3b66b13c30d\">\n<li style=\"font-style:normal;font-weight:400\"><strong>Genelle Lunken<\/strong>, UBC, Principal Investigator<\/li>\n\n\n\n<li style=\"font-style:normal;font-weight:400\"><strong>Email:<\/strong> <a href=\"mailto:calina.ibd.ubc.ca\" title=\"\">calina.ibd.ubc.ca<\/a><\/li>\n\n\n\n<li><strong>Phone number:<\/strong> (+1) 604-441-4992<\/li>\n<\/ul>\n\n\n\n<p class=\"has-text-primary-color has-text-color has-link-color has-system-font-font-family has-large-font-size wp-elements-d98c4a2b74062e8a8f88a833dd03eb3a wp-block-paragraph\" style=\"font-style:normal;font-weight:300\">Learn more: Visit <a href=\"https:\/\/clinicaltrials.gov\/study\/NCT07385807\" target=\"_blank\" rel=\"noopener\" title=\"\">ClinicalTrials.gov<\/a> For More Information<\/p>\n<\/div>\n\n\n\n<div class=\"wp-block-group alignfull has-tertiary-background-color has-background has-global-padding is-layout-constrained wp-block-group-is-layout-constrained\" style=\"margin-bottom:0;padding-top:var(--wp--preset--spacing--large);padding-bottom:var(--wp--preset--spacing--large)\">\n<figure class=\"wp-block-image size-full\"><img loading=\"lazy\" decoding=\"async\" width=\"851\" height=\"315\" src=\"https:\/\/ibdcentrebc.ca\/lunkenlab\/wp-content\/uploads\/2026\/03\/All-Logos-1.png\" alt=\"\" class=\"wp-image-1786\" srcset=\"https:\/\/ibdcentrebc.ca\/lunkenlab\/wp-content\/uploads\/2026\/03\/All-Logos-1.png 851w, https:\/\/ibdcentrebc.ca\/lunkenlab\/wp-content\/uploads\/2026\/03\/All-Logos-1-300x111.png 300w, https:\/\/ibdcentrebc.ca\/lunkenlab\/wp-content\/uploads\/2026\/03\/All-Logos-1-768x284.png 768w\" sizes=\"auto, (max-width: 851px) 100vw, 851px\" \/><\/figure>\n<\/div>\n\n\n\n<p class=\"wp-block-paragraph\"><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Calina-IBd Study Purpose of THe Study The goal of this observational pilot study is to explore how inflammatory bowel disease (IBD) during pregnancy may influence [&hellip;]<\/p>\n","protected":false},"author":3,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"footnotes":"","_links_to":"","_links_to_target":""},"class_list":["post-1693","page","type-page","status-publish","hentry"],"aioseo_notices":[],"_links":{"self":[{"href":"https:\/\/ibdcentrebc.ca\/lunkenlab\/wp-json\/wp\/v2\/pages\/1693","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/ibdcentrebc.ca\/lunkenlab\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/ibdcentrebc.ca\/lunkenlab\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/ibdcentrebc.ca\/lunkenlab\/wp-json\/wp\/v2\/users\/3"}],"replies":[{"embeddable":true,"href":"https:\/\/ibdcentrebc.ca\/lunkenlab\/wp-json\/wp\/v2\/comments?post=1693"}],"version-history":[{"count":30,"href":"https:\/\/ibdcentrebc.ca\/lunkenlab\/wp-json\/wp\/v2\/pages\/1693\/revisions"}],"predecessor-version":[{"id":1889,"href":"https:\/\/ibdcentrebc.ca\/lunkenlab\/wp-json\/wp\/v2\/pages\/1693\/revisions\/1889"}],"wp:attachment":[{"href":"https:\/\/ibdcentrebc.ca\/lunkenlab\/wp-json\/wp\/v2\/media?parent=1693"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}